A. A farmer started having difficulty breathing and vigour cramping, with pop off muscle control and some rigidity. He recalled that the symptoms started soon by and by he started using a new pesticide in the fields. The bit of normal muscle physiology at the cellular level. 1.A beat natural covering off neuron wall sockets acetylcholine (Ach) molecules as a transmitter. 2.Ach diffuses from the typeface determination and attaches to a protein receptor in the muscle cell membrane. 3.The Ach receptors be randy to open sodium ion (Na+) gates in the membrane, and Na+ rushes in across the membrane. 4.This depolarizes the membrane and causes a bleed somewhat of calcium ions (Ca2+) from the cells sarcoplasmic second stomach (SR). 5.Ca2+ attaches to troponin protein, which is on the actin, and causes the actin to rotate and move the interfering tropomyosin out of the track (tropomyosin sits in its resting position and blocks the fundamental interaction of actin with myosin, the main muscle proteins). 6. at once tropomyosin is moved, actin and myosin interact. Myosin has the ATPase enzyme to release the vim needed to contract. 7.The pivoting heads of the myosin pulls the actin along from opposite sides, where the actin units atomic number 18 anchored. This shortens the muscle as individual units (sarcomeres) argon contracted. 8.
Muscle concretion continues for the short pointedness of time that the Ach is bound to the receptor, and continued release of Ach by the nerve cell can keep the muscle contracting (tetany = a tetanic contraction). A single release of Ach woul d cause a twitch 9.Because to regulate mu! scle contractions, the Ach is chop-chop degraded by the enzyme acetylcholine esterase, and muscles relax as all the activities above revert back to their original state (K+ moves out to repolarize the membrane). In normal movements, our muscles are stimulated many times in quick chronological succession to achieve a smooth, sustained contraction. attached motor units are stimulated asynchronously at a absolute frequency that go forth produce...If you want to get a full essay, tack in concert it on our website: OrderCustomPaper.com
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